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Scientists' Understanding of Anxiety is Radically Evolving—But How Long Will it Take for Treatments to Catch Up?

Do dreams have deeper meanings? Let's ask science

We've all had crazy dreams, but do they actually mean anything? Dr. Brendan Depue and Dr. Nick Hindy share their take on what we see when we're asleep.

You probably multitask every day. Here's why Dr. Brendan Depue says you shouldn't

Multitasking is just part of our culture now. But a science professor at UofL says that it isn't a real thing.

Lindsay Knight and Leigh Brosof receive the Research and Creative Activities Grant from University of Louisville

In this collaborative research project on eating disorders (ED), Lindsay and Leigh will investigate how neurobiology changes following a 10-week imaginal exposure therapy intervention adapted to target ED fears.

Dr. Brendan Depue discusses fear and anxiety on UofL Today

Brain’s “Brakes” Suppress Unwanted Thoughts

Dr. Brendan Depue commented on researchers identifying a new target for disorders such as PTSD and schizophrenia.

Lindsay Knight receives an APA Dissertation Research Award!

Lindsay's dissertation research is investigating the brain mechanisms utilized to effectively control anxious feelings, specifically the prefrontal mechanisms that downregulate reactivity of the bed nucleus of the stria terminalis (BNST).

Teodora Stoica receives the Next Generation Award!

Teodora Stoica was honored at Society for Neuroscience 2018 with the Next Generation Award for her dedication in providing outreach and research opportunities to young students from underrepresented backgrounds through her Louisville Science Pathways program.

Dr. Brendan Depue awarded the NARSAD Young Investigator Grant

The Brain & Behavior Research Foundation Young Investigator Grants provide each scientist funds enabling promising investigators to either extend research fellowship training or begin careers as independent research faculty. The goal of the YI program is to help researchers launch careers in neuroscience and psychiatry and gather pilot data to apply for larger federal and university grants. 

Detailed information on the foundation and the grant can be found below.

Using Screams to Examine Differences Between Fear and Anxiety in the Human Brain

Work in rodents suggests that the main differentiation lies in the distinct roles of two brain regions, the amygdala and the bed nucleus of the stria-terminalis (BNST), when the animal is experiencing only fear or only anxiety. Based on these findings, the question then becomes: Is it possible that the complexity of human emotion is similarly differentiated between these two structures as it is in rodents?

Importance of controlling for alcohol use when exploring marijuana’s impact on brain structure

Although some studies indicate that marijuana use is associated with changes in brain structure, other studies have not found such a relationship. Recent research funded by NIDAand NIAAA explores whether alcohol use may play some role in these discrepant results.

CU: Trauma can be forgotten

CU study finds practice may help put painful thoughts out of mind.

Fuggedaboudit, or Remember—It Just Takes Practice

Conscious memory manipulation could aid in designing both clinical treatments and new drug targets for patients suffering from phobias and post-traumatic stress.

You can forget the past

Researchers have confirmed what common wisdom has long held -- that people can suppress emotionally troubling memories -- and said on Thursday they have sketched out how the brain accomplishes this. They said their findings might lead to a way to help patients with post-traumatic stress disorder or anxiety to gain control of debilitating memories.

Forcing Yourself to Forget

While the old saw says that it is easier to forgive than to forget, new research reveals that the latter may still be possible, even for very emotional memories. Researchers at the University of Colorado worked with 16 subjects to see if they could actively suppress their own memories. To do this, the researchers had subjects memorize 40 pairs of pictures, which were chosen because they provoked emotional responses.

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